what is selphyl & selphyller?
At Revolution Aesthetics, we’re always looking for the most advanced ways to rejuvenate the skin naturally—and Selphyl is one of our favorite solutions.
Selphyl is a next-generation regenerative treatment that uses your body’s own platelet-rich fibrin matrix (PRFM), a more advanced form of PRP (platelet-rich plasma), to restore volume, improve skin texture, and boost collagen production. This treatment is completely natural and drug-free, using only your own blood to activate healing and tissue regeneration.
How Does it Work?
During your appointment, we draw a small sample of your blood and process it using a special system that separates and purifies your platelets. What makes Selphyl different from traditional PRP is the addition of calcium chloride, which converts the PRP into PRFM—creating a more stable “liquid gold” solution that releases growth factors slowly over several days (instead of just hours).
This allows for longer-lasting, more targeted results with:
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Greater collagen stimulation
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Improved hydration and elasticity
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Firmer, smoother skin
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Minimal discomfort with no synthetic ingredients
What is selphyller?
Selphyller is the second step in the Selphyl system. After converting your PRP into PRFM, we can heat the solution slightly to turn it into a natural, volumizing gel—perfect for areas that need subtle lift or contouring.
It’s an excellent option for patients who want a filler alternative that looks soft, natural, and regenerative.
Why do Patients (and Providers) Love It?
Unlike synthetic fillers, PRFM carries no risk of allergic reactions and is safe to use in delicate areas. In fact, Selphyl is one of the only treatments we recommend for the under-eye (tear trough) area due to its safety and effectiveness
Best treatment areas for selphyl / selphyller
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Tear troughs (under-eye hollows)
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Fine lines and wrinkles
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Smile lines / nasolabial folds
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Jawline and cheeks (for subtle volume)
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Neck and décolleté
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Acne scars or uneven texture
- Hair follicles for hair restoration
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Is selphyl right for you?
If you’re looking for a natural, non-surgical way to refresh your appearance, improve skin tone and texture, and restore youthful volume—Selphyl or Selphyller may be your perfect match. It’s safe, effective, and backed by science.
Want to learn more or see if you’re a good candidate? Schedule a consultation today—we’re happy to guide you through your options!
Related Services
Microneedling
Dysport & Xeomin
Skincare
